HIV/AIDS Research at Northwestern

April 2014 HIV cure-related Special Events:

In April 2014, Timothy Ray Brown (previously known as “the Berlin patient”) was invited to Chicago to mark the 7th year that he has been off-antiretrovirals following a unique stem cell transplant. He is felt by scientists to be the first person cured of HIV infection.

The Northwestern HIV Translational Research Center, the IMPACT LGBT Health and Development Program @ Northwestern, the AIDS Foundation of Chicago, and the Chicago Department of Public Health organized Mr. Brown’s visit to Chicago in collaboration with the Timothy Ray Brown Foundation of the World AIDS Institute and “Chicago Uniting for Research to End HIV (CURE HIV)”. CURE HIV is a committee of representatives of the organizations named above and following additional organizations:  Brothers Health Collective, Center on Halsted, Howard Brown Health Center, Loyola University, Test Positive Aware Network, University of Chicago and its Chicago Center for HIV Elimination, University of Illinois at Chicago, and Vida/SIDA.

Curing HIV-Only A Start
Community Forum on HIV Cure Research
with Timothy Ray Brown, The Man Who Once Had HIV
Wednesday, April 23, 2014
Chicago Cultural Center
Watch the video

HIV Cure Research: Can It Contribute to Slowing the Epidemic?
Workshop to Foster Research on More Feasible HIV Cure Strategies
Which Will Synergize Efforts to Improve HIV Prevention
Thursday, April 24, 2014
Northwestern Memorial Hospital

Session 1 - Setting the Stage: (Video)
Introduction to the Workshop and HIV Cure Research - Richard D'Aquila, MD (Northwestern University)

The Current Status of the HIV Epidemic in Chicago - Nikhil Prachand, MPH (Chicago Dept. of Public Health)

Session 2 - Sustained remissions after very early antiretroviral therapy (ART): (Video)
Sustained remission of HIV after early antiretroviral therapy (ART) of an infant ("The Mississippi baby") - Deborah Persaud, MD (John Hopkins University) 

Sustained remissions of HIV after early ART of adults (VISCONTI) - Asier Sáez-Cirión, PhD (Institut Pasteur)

Q&A moderated by Ellen Chadwick, MD and Richard D'Aquila, MD (Northwestern University)

Session 3 - Risks and interventions for new HIV infections: (Video)
Syndemic among gay, bisexual, and transgendered youth in Chicago - Brian Mustanski, PhD (Northwestern University)

Pre-exposure prophylaxis (PrEP) for HIV - Sybil Hosek, PhD (Stroger Hospital of Cook County)

Network approaches to care access, retention, and ART initiation in young gay and bisexual men - John Schneider, MD. (University of Chicago)

Q&A moderated by Robert Garofalo, MD (Northwestern University)

Session 4 - Other research strategies for sustained remission: (Video)
Allogeneic transplant of HIV-susceptible hematopoietic stem cells under ART, the "Boston patients" - Timothy Henrich, MD (Harvard Medical School)

Immunological evidence of ongoing replication during ART and unsuccessful trials of cure in chronically infected subjects -Robert Murphy, MD (Northwestern University)

Summary of Community Forum and Special Address : (Video)
Summary of Community Forum - Amy Johnson (AIDS Foundation of Chicago)
Special Address from Timothy Ray Brown

Session 5 - Understanding immune mechanisms of remission: (Video)
Effect of ART interruptions on HIV control in children - William Borkowsky, MD (New York University)

Interferon, ART interruption, and HIV control in adults - Luis Montaner, D.V.M., M.sc., D. Phil. (Wistar Institute)

Increased APOBEC3 (A3) editing of HIV genomes: Does it help or hurt HIV? - Reuben Harris PhD (University of Minnesota)

Preserving and Repleting Defenses: Building on the 'restorative window' - Richard D'Aquila, MD (Northwestern University)

Q&A moderated by Thomas Hope, PhD (Northwestern University)

Concluding comments and discussion - David Munar (Howard Brown Health Center), Brian Mustanski, Richard D’Aquila

Northwestern HIV/AIDS Research web sites: